What kinds of methods exist for applying the laws of chromatographic separation to the use of this technique as an industrial device in the purification and separation of materials? Devices for chromatography found in scientific laboratories are mainly used for liquid column chromatography and gas chromatography. These devices are primarily for use in analysis, and are of a very small scale when compared with typical industrial devices.

In the chromatography devices used for analysis, columns with 100 [mm] diameter are called large-scale preparative columns. In recent years, there have been cases in which chromatography devices using preparative columns of this size have been applied in industrial settings, especially in the production of medicine. However, there is not much difference in the mechanism of separation employed in chromatographical devices with preparative columns and that of chromatographical devices used for analysis. Column diameter: 1800 [mm].

Among the chromatographic separation devices supplied by ORGANO, there are some which use comparatively much larger columns, with diameters up to 3200 [mm]. Chromatographic devices of this size have undergone a high degree of modification so as to be useful in industrial settings. In particular, ORGANO has applied its expertise in advancing the industrial uses of the simulated moving-bed method of chromatographic separation. Next, let's consider the three basic methods of chromatographic separation: the fixed-bed method, the moving-bed method, and the simulated moving-bed method.